Technical knowledge: No technical knowledge is required for running a managed server. When you need to do something technical all you have to do is contact support and let the skilled technical support operators handle the rest. With an unmanaged server you need to have server administration skills and love working in the command line otherwise it will be very difficult to administer your server efficiently.
Deploy a full range of open-source and community-driven software solutions on Azure. Choose from a full range of Linux distributions like Red Hat, Ubuntu, SUSE, and community-driven solutions like Chef, Puppet, and Docker. Deploy virtual machines for other products like Oracle Database and Oracle WebLogic Server. Azure is open with lots of options.
A VPS runs its own copy of an operating system (OS), and customers may have superuser-level access to that operating system instance, so they can install almost any software that runs on that OS. For many purposes they are functionally equivalent to a dedicated physical server, and being software-defined, are able to be much more easily created and configured. They are priced much lower than an equivalent physical server. However, as they share the underlying physical hardware with other VPSes, performance may be lower, depending on the workload of any other executing virtual machines.